Luísa from Nothing, born Matilde Boshoff in 1911, is the last living heiress of Nothing, a vast estate in the wine countryside north of the Portuguese capital. Without heirs of her own, the only way to save Nothing from the nothingness of disappearance is to accept living. In anonymous company, Luísa tells the story of Nothing and the paradox of a place name that nullifies existence. Luísa is also a non-existence, with a name she never took but in which she has lived from birth.
Going back to the early 19th century when Nothing was created out of the chaos of the Napoleonic Invasions, Luísa traces the story of her family and its intersection with Portuguese and world history in a place where oddities and unpronounceable possibilities were always as natural occurrences as ghosts and werewolves. After a life of losses and brushes with the unfathomable, Luísa realises Nothing is her own eternal self.